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Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains.

机译：Hsp90-Cdc37伴侣与Cdk4客户蛋白结合的原子模拟和基于网络的建模：通过利用内在动态激酶结构域的弱点来陪伴激酶客户的机制。

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Josh Czemeres; Kurt Buse; Gennady M Verkhivker;
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年度 2017
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1. Functional Role and Hierarchy of the Intermolecular Interactions in Binding of Protein Kinase Clients to the Hsp90–Cdc37 Chaperone: Structure-Based Network Modeling of Allosteric Regulation [J] . Gabrielle Stetz, Gennady M. Verkhivker Journal of chemical information and modeling . 2018,第2期

机译：蛋白质激酶客户结合到HSP90-CDC37伴侣的分子间相互作用的功能作用和层次分子：基于结构的构旋调节网络建模
2. Allosteric Mechanism of the Hsp90 Chaperone Interactions with Cochaperones and Client Proteins by Modulating Communication Spines of Coupled Regulatory Switches: Integrative Atomistic Modeling of Hsp90 Signaling in Dynamic Interaction Networks [J] . Astl Lindy, Stetz Gabrielle, Verkhivker Gennady M. Journal of chemical information and modeling . 2020,第7期

机译：通过调制耦合调节器开关的通信刺与Cochaperone和客户端蛋白的HSP90伴侣蛋白的变构机制：动态交互网络中HSP90信令的综合原子模型
3. Structural Bioinformatics and Protein Docking Analysis of the Molecular Chaperone-Kinase Interactions: Towards Allosteric Inhibition of Protein Kinases by Targeting the Hsp90-Cdc37 Chaperone Machinery [J] . Elizabeth Berrigan, Gennady Verkhivker, Kristin Blacklock, Pharmaceuticals . 2013,第11期

机译：分子伴侣-激酶相互作用的结构生物信息学和蛋白质对接分析：通过靶向Hsp90-Cdc37伴侣机械对蛋白质激酶的变构抑制。
4. Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains [O] . Josh Czemeres, Kurt Buse, Gennady M. Verkhivker 2011

机译：Hsp90-Cdc37伴侣蛋白与Cdk4客户蛋白结合的原子模拟和基于网络的建模：通过利用内在动态激酶结构域的弱点来伴侣蛋白激酶客户的机制
5. Ensemble-based modeling and rigidity decomposition of allosteric interaction networks and communication pathways in cyclin-dependent kinases: Differentiating kinase clients of the Hsp90-Cdc37 chaperone. [O] . Gabrielle Stetz, Amanda Tse, Gennady M Verkhivker 2017

机译：基于集合的建模和变构相互作用网络的刚性分解和细胞周期蛋白依赖性激酶的通信途径：区分Hsp90-Cdc37伴侣的激酶客户。

Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains.

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